Open Science and Reporting Animal Studies: Who's Accountable?

Open Science and Reporting Animal Studies: Who's Accountable?

What responsibility do scientists have to report the experimental work and analyses they do on animals fully and transparently, and what responsibilities do funders, journal editors, and reviewers have to ensure that what is reported is done so appropriately? While the answer to both of these questions might seem obvious, the accumulating evidence suggests that the actual reporting done in publ...

Reporting Animal Studies: Good Science and a Duty of Care

Estimates of the number of non-human animals used in research vary between 10 million and 50 million [1,2]. As a publisher, we receive submissions from scores of research groups in numerous different countries that report experimental results or observational data about a huge variety of organisms. Each field, each location, each type of experiment, and each organism may carry a different set o...

Reporting of Results from Animal Studies

One of the key elements of the scientific process is reproducibility: Experimental results generated in one laboratory must be repro­ ducible by others working independently. Therefore, it is of concern to us as editors of a major scientific journal to learn that only 6 of 53 " landmark " preclinical cancer studies could be reproduced (Begley and Ellis 2012). In addition, Prinz et al. (2011) re...

Nutrigenomics and its Applications in Animal Science

Nutrigenomics applies genomic technologies to study how nutrients affect expression of genes. With the advent of the post genomic era and with the use of functional genomic tools, the new strategies for evaluating the effects of nutrition on production efficiency and nutrient utilization are becoming available. Nutrigenomics plays an efficient role in various fields of animal health like nutrit...

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